| PhytoCAT-ID | Phytochemical name or plant extracts | Source of phytochemicals or plant Extracts | Target gene or protein | Cell line/ mice model |
|---|---|---|---|---|
| PhytoCAT-66 | Chimnitensin A | Chimonanthus nitens Oliv | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-67 | Chimnitensin B | Chimonanthus nitens | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-68 | Chimnitensin C | Chimonanthus nitens | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-69 | Chimnitensin D | Chimonanthus nitens | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-70 | Chimnitensin E | Chimonanthus nitens | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-71 | Chimnitensin F | Chimonanthus nitens | NA | MDA-MB-468, MDA-MB-231 |
| PhytoCAT-77 | β-dihydroagarofuran-type sesquiterpene (MD-6) | Maytenus disticha | NA | MCF-7, PC9, C4-2B |
| PhytoCAT-78 | (1α,2α,8β,9β)-1,8-bis(acetyloxy)-2,9-bis(benzoyloxy)-14-hydroxy-β-dihydroagarofuran | Celastrus paniculatus | AKT, NF-κB, p53, MAPK | MCF-7 |
| PhytoCAT-98 | Albicanol | Dryopteris fragrans | NA | A549, MCF-7, HepG2 |
| PhytoCAT-119 | Codonolactone | Atractylodes lancea | Runx2 | MDA-MB-468, MDA-MB-231, Five-to 6-week-old female NOD/SCID mice |
| PhytoCAT-125 | 13-O-acetylsolstitialin A | Centaurea cyanus | Bax, Bcl-2, Cyclin D1, CDK-4 | MCF-7, MDA-MB-231 |
| PhytoCAT-129 | Brevilin A | Centipeda minima | AKT, mTOR, STAT-3 | MDA-MB-231, MDA-MB-468, MCF-7 |
| PhytoCAT-145 | Eupalinolide O | Eupatorium lindleyanum | Cyclin B1, cdc2 | MDA-MB-468 |
| PhytoCAT-147 | Helenalin | Psilostrophe cooperi | Telomerase | T47D |
| PhytoCAT-153 | Britannin | Inula aucheriana | Bcl-2, Bax, p53 | MCF-7, MDA-MB-468 |
| PhytoCAT-157 | Fischerisin A | Ligularia fischeri | NA | MCF-7, KB |
| PhytoCAT-158 | fischerisin B | Ligularia fischeri | NA | MCF-7, KB |
| PhytoCAT-159 | 4beta,14-dihydro-3-dehydrozaluzanin C | Onopordum acanthium | NA | HeLa, MCF-7 , A431 |
| PhytoCAT-168 | 7β-(3-Ethyl-cis-crotonoyloxy)-1α-(2-methylbutyryloxy)-3,14-dehydro-Z-notonipetranone (ECN) | Tussilago farfara | STAT-3 | MDA-MB-231 |
| PhytoCAT-171 | Vernolactone | Vernonia zeylanica | Survivin, p53, Bax, Caspase 3, Caspase 7 | MCF -7, MDA-MB-231, SKBR-3 |
| PhytoCAT-262 | Gaillardin | Gaillardia pulchella | Bax, p53, Bcl-2 | MCF-7, MDA-MB-468 |
| PhytoCAT-802 | Eupatolide | Inula britannica | Vimentin , E-cadherin, EMT | MCF-7, MDA-MB-231 and MDA-MB-453 |
| PhytoCAT-898 | Ferulin C | Ferula ferulaeoides | NA | MCF-7 and MDA-MB-231 |
| PhytoCAT-1025 | Artahongkongol A | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1026 | 1a-hydroxy-5,11- eudesmadiene | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1027 | 5-eudesmene-1b,4a-diol | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1028 | 1b,11-dihydroxy-5- eudesmene | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1029 | 1b-hydroxy-11-methoxy-5- eudesmene | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1030 | 2a-hydroxy pterodontic acid | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1031 | 1b,9b-dihydroxy-4aH-eudesma-5,11(13)- dien-12-oic acid | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1032 | 1b,3a-dihydroxyeudesma-5,11(13)-dien-12-oic acid | Artabotrys hongkongensis | NA | MCF-7, HL-60, SMMC-7721, A-549, SW480 |
| PhytoCAT-1036 | (4α,5α,8β,10β)-4,10-dihydroxy-1,11(13)-guaidien-12,8-olide | Chrysophthalmum montanum | NA | MCF-7, MDA-MB 231, HT-29, PC3 |
| PhytoCAT-1049 | Costunolide | Costus speciosus | p21WAF1, Cdc2, Cyclin B1, Fas, Caspase 8, Caspase 3, Cyclin D1, Cyclin D3, CDK-4, CDK-6, p18 INK4c, p27 KIP1 | MDA-MB-231, MCF-7 |
| PhytoCAT-1100 | F1012-2 | Eupatorium lindleyanum | Cyclin B1, cdc2, p21, p-cdc2. | MDA-MB-231, MDA-MB-468, MDA-MB-231 xenografts |
| PhytoCAT-1140 | Dihydro-β-agarofuran | Maytenus cuzcoina, Maytenus canariensis, Maytenus magellanica, Maytenus chubutensis | P-gp | MDA-MB-231, NIH-3T3, NIH-3T3 MDR-G185, MDCKII, MDCKII-MRP2,MDA-MB-231-BCRP |
| PhytoCAT-1211 | (-)-Xanthatin | Xanthium strumarium | GADD45γ, c-fos | MDA-MB-231 |
| PhytoCAT-1325 | Artemisinin | Artemisia annua | CDK4, Cyclin-B1, Cyclin D1, Cyclin E, ER , miR-34a ,TSP50 | MCF-7, MDA-MB-231, P-388, A-549, HT-29, KB |
| PhytoCAT-1389 | Lineariifolianoid E | Inula lineariifolia Turcz | NA | MCF-7, MDA-MB-231 |
| PhytoCAT-1471 | Caroguaianolide A | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1472 | Caroguaianolide B | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1473 | Caroguaianolide C | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1474 | Akihalin | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1475 | 4β-hydroxy,10β-hydroperoxyl,5αH,7αH,8βH-guaia-1,11(13)-dien-8α,12-olide | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1476 | (3aR,4aS,5S,7aS,8S,9aR)-5-hydroxy-4a,8-dimethyl-3-methylen-decahydroazuleno[6,5-b]furan-2(3H)-on | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1477 | 2-desoxy-4-epi-pulchellin | Carpesium abrotanoides | NA | HGC-27, MDA-MB-231 |
| PhytoCAT-1500 | β-Caryophyllene oxide | Psidium guajava, Origanum vulgare, Cinnamomum spp, Eugenia caryophyllata, Piper nigrum | Bcl-2, Bcl-xL, IAP-1, IAP-2, COX-2, VEGF, p53, p21, Cyclin D1 | PC-3, MCF-7, MCF-7, MDA-MB-231, Ehrlich solid tumor bearing mice |
| PhytoCAT-1686 | Santonin | NA | NA | SKBR-3 |
| PhytoCAT-1722 | Arnicolide D | Centipeda minima | NA | MDA-MB-231 xenograft mouse model, MDA-MB-231, MDA-MB-468 |
| PhytoCAT-1735 | Deoxyelephantopin | Elephantopus scaber | p21(Waf1/Cip1), MMP9, NF-kB | MDA-MB-231, MCF-7 |
| PhytoCAT-1790 | Songaricalarin D | Ligularia songarica | NA | A-549, MCF-7, KB, and KBVIN |
| PhytoCAT-1877 | Vernonilide A | Vernonia anthelmintica | NA | A549, HeLa, MDA-MB-231 |
| PhytoCAT-1878 | Vernodalin | Vernonia anthelmintica, Vernonia extensa, Centratherum anthelminticum (L) | NA | HepG2, MCF-7, MDA-MB-231, HeLa, A549 |
| PhytoCAT-1879 | Vernomelitensin | Vernonia anthelmintica, Vernonia guineensis Benth (Asteraceae) | NA | MDA-MB-231, MCF-7, HCT-116, HL-60, A549, A375, OVCAR3, PC-3, DU-145 |
| PhytoCAT-1880 | Vernolepin | Vernonia anthelmintica | NA | HeLa, MDA-MB-231, HepG2 |
| PhytoCAT-1976 | Parthenolide | Tanacetum parthenium | AMPK, JNK, NF-κB, STAT-3, MAP kinase, FAK1 | Hs605T, MCF-7, SiHa, MCF-7/HER2, MDA-MB-231, BT-474 |
| PhytoCAT-1993 | 2β-hydroxy-8β-[5′-hydroxytigloyloxy]-costunolide | Eupatorium fortunei | NA | PC3, SKOV3, A549, MCF-7, HEp-2 |
| PhytoCAT-2018 | Trans-nerolidol (NER) | Myrica rubra | NA | MCF-7, MDA-MB-231, Ehrlich solid tumor bearing mice |
| PhytoCAT-2112 | Budlein A methylacrylate (BAM) | Helianthus genus | IκBα kinase, exportin-1 | MDA-MB-231, MDA-MB-453, MDA-MB-435, MDA-MB-468, HCC1937, HCC2218, HCC1954, HCC202, HCC1500, MCF-7 |
| PhytoCAT-2117 | Xanthinosin | Xanthium strumarium | DR4, DR5, p53, CHOP, Bax, Caspase 3, Caspase 8, Caspase 9, Bcl-2 | DLD1, DU145, HeLa, MCF-7, MDA-MB-231 |
| PhytoCAT-2133 | Caroguaianolide D | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2134 | Caroguaianolide E | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2135 | 4α-hydroxy-9β,10β-epoxy-1βH,5αH-guaia11(13)-en-8α,12-olide | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2136 | Carabrolactone B | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2137 | 4α-hydroxy1βH-guaia-9,11(13)-dien-12,8α-olide | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2138 | 8-epi-inuviscolide | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |
| PhytoCAT-2139 | Inuviscolide | Carpesium abrotanoides | NA | MDA-MB-231, HGC-27 |