| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1389 | |
| Phytochemical name or plant extracts | Lineariifolianoid E | |
| PMID | 24044895 | |
| Literature evidence | Further studies also presented that lineariifolianoid E had significant, dose-dependent effects on cell cycle progression and apoptosis in breast cancer cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Sesquiterpene | |
| Source of phytochemicals or plant Extracts | Inula lineariifolia Turcz | |
| Geographical availability | Amur, China North-Central, China South-Central, China Southeast, Japan, Khabarovsk, Manchuria, Mongolia, Primorye | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.56 µM against MCF-7 2.75 µM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, MDA-MB-231 | |
| Additional information | Induction of cell cycle arrest and apoptosis would be key mechanisms of action. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:225963-1 | |
| Safety | NA |