Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-67 | |
Phytochemical name or plant extracts | Chimnitensin B | |
PMID | 34403777 | |
Literature evidence | In vitro MTT assay showed that all six compounds had cytotoxicity against two selected human breast cancer cell lines (MDA-MB-468 and MDA-MB-231), which indicate their potential of developing into anticancer drugs. | |
IUPAC name | (1S,3S,4R,4aS,8aR)-1,6-dimethyl-4-(propan-2-yl)-1,2,3,4,4a,7,8,8a-octahydronaphthalene-1,3-diol | |
Phytochemicals’ class or type of plant extracts | Sesquiterpene | |
Source of phytochemicals or plant Extracts | Chimonanthus nitens | |
Geographical availability | China North-Central, China South-Central, China Southeast | |
Plant parts | Leaves | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | NA | |
Potency | The results showed that compounds 1–6 revealed varying cytotoxicity degrees against these human breast cancer cell lines. | |
Cell line/ mice model | MDA-MB-468, MDA-MB-231 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:139245-1 | |
Safety | NA |