| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1877 | |
| Phytochemical name or plant extracts | Vernonilide A | |
| PMID | 27311895 | |
| Literature evidence | In addition, 5 exhibited significant antiproliferative activities against HeLa and MDA-MB-231 cells, with IC50 values ranging from 1.90 to 2.20μM. | |
| IUPAC name | (3aR,4S,6aR,9R,9aR,9bR)-9-(hydroxymethyl)-3,6-dimethylidene-2-oxo-dodecahydroazuleno[4,5-b]furan-4-yl 2-(hydroxymethyl)prop-2-enoate | |
| Phytochemicals’ class or type of plant extracts | Sesquiterpene lactone | |
| Source of phytochemicals or plant Extracts | Vernonia anthelmintica | |
| Geographical availability | Afghanistan, Botswana, China South-Central, India, Kenya, Laos, Malawi, Mozambique, Myanmar, Namibia, Nepal, Pakistan, Sri Lanka, Tanzania, Uganda, Vietnam, West Himalaya, Zambia, Zaïre, Zimbabwe | |
| Plant parts | Seeds | |
| Other cancers | Breast cancer, Cervical cancer, Lung Cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.25 μM against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | A549, HeLa, MDA-MB-231 | |
| Additional information | Exhibits strong antiproliferative activities against three human cancer cell lines (A549, HeLa, and MDA-MB-231) | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | NA | |
| Safety | NA |