| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-157 | |
| Phytochemical name or plant extracts | Fischerisin A | |
| PMID | 21467686 | |
| Literature evidence | China. wdxie@sdu.edu.cn During the course of screening natural sesquiterpenoids for new antitumor agents, two novel compounds, fischerisin A (1) and fischerisin B (2), were isolated from the roots of Ligularia fischeri. | |
| IUPAC name | (4aS,5R,8aR)-2-[(2E)-1-(2,5-dihydroxy-3-methylphenyl)-3,7-dimethylocta-2,6-dienyl]-3,4a,5-trimethyl-4,5,8a,9-tetrahydrobenzo[f][1]benzofuran-6-one | |
| Phytochemicals’ class or type of plant extracts | Sesquiterpene | |
| Source of phytochemicals or plant Extracts | Ligularia fischeri | |
| Geographical availability | Amur, Assam, Buryatiya, China North-Central, China South-Central, China Southeast, Chita, East Himalaya, Inner Mongolia, Japan, Khabarovsk, Korea, Manchuria, Mongolia, Myanmar, Nepal, Pakistan, Primorye, Sakhalin, West Himalaya | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Epidermoid cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 10.2 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, KB | |
| Additional information | NA | |
| PubChem ID | 52952874 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:230742-1 | |
| Safety | NA |