| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1993 | |
| Phytochemical name or plant extracts | 2β-hydroxy-8β-[5′-hydroxytigloyloxy]-costunolide | |
| PMID | 32984720 | |
| Literature evidence | In the present study, the rapid annotation of the mixture of compounds in a fraction by the NMR-based machine learning tool helped the targeted isolation of bioactive compounds from natural products. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Sesquiterpene lactone | |
| Source of phytochemicals or plant Extracts | Eupatorium fortunei | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Hainan | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 5.8 ± 0.1 µM against MCF-7 | |
| Potency | Compound 7 showed good cytotoxicity with IC50 values of 5.8 ± 0.1 μM against breast cancer cells, MCF-7. Compound 7 is 2β-hydroxy-8β-[5′-hydroxytigloyloxy]-costunolide. | |
| Cell line/ mice model | PC3, SKOV3, A549, MCF-7, HEp-2 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:205930-1 | |
| Safety | NA |