| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1823 | |
| Phytochemical name or plant extracts | p-hydroxybenzoic acid | |
| PMID | 24752205 | |
| Literature evidence | Importantly, vanillic acid content correlated significantly with anticancer activity in PC-3 and MCF-7 cells (p<0.01, p<0.05 respectively). | |
| IUPAC name | 4-hydroxybenzoic acid | |
| Phytochemicals’ class or type of plant extracts | Phenolic acid | |
| Source of phytochemicals or plant Extracts | Tetrastigma hemsleyanum Honey | |
| Geographical availability | China South-Central, China Southeast, Taiwan, Tibet | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | In conclusion, Greek honeys are rich in phenolic acids, in particular protocatechuic and p-hydroxybenzoic acid and exhibit significant antioxidant, anticancer and antiatherogenic activities which may be attributed, at least in part, to their phenolic acid content. | |
| Cell line/ mice model | MCF-7, HeLa | |
| Additional information | Parabens are alkyl esters of p-hydroxybenzoic acid used widely as antimicrobial preservatives in consumer products, including pharmaceuticals, foods and cosmetics. | |
| PubChem ID | 135 | |
| Additional PMIDs | 27393430 23049233 29984179 31905725 23857141 24752205 33799523 25038699 29382154 24652746 24481588 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:767683-1 | |
| Safety | corrosive in pubchem database |