Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-499 | |
Phytochemical name or plant extracts | erythrodiol-3-acetate (HU-1) | |
PMID | 30475646 | |
Literature evidence | HU-2 has potential for development as a novel anti-inflammatory and anticancer agent. | |
IUPAC name | [(3S,6aR,6bS,8aS,12aS,14aR,14bR)-8a-(hydroxymethyl)-4,4,6a,6b,11,11,14b-heptamethyl-1,2,3,4a,5,6,7,8,9,10,12,12a,14,14a-tetradecahydropicen-3-yl] acetate | |
Phytochemicals’ class or type of plant extracts | Triterpenoid | |
Source of phytochemicals or plant Extracts | Humboldtia unijuga | |
Geographical availability | India | |
Plant parts | Root | |
Other cancers | Breast cancer | |
Target gene or protein | Caspase 7 | |
Gene or Protein evidence | HU-1 exhibited a dose dependent effect on caspase 7 gene in both cell lines while HU-2 was more effective in A431 | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | MCF-7, A431 | |
Additional information | NA | |
PubChem ID | 118796402 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:498715-1 | |
Safety | NA |