| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1242 | |
| Phytochemical name or plant extracts | Zantholic acid | |
| PMID | 23802991 | |
| Literature evidence | The cytotoxic activity of zantholic acid against a panel of cancer cell lines was evaluated using the MTT assay. | |
| IUPAC name | (4R,7R)-8-carboxy-7,9-dihydroxy-trans-menthane | |
| Phytochemicals’ class or type of plant extracts | Menthane monoterpenoid | |
| Source of phytochemicals or plant Extracts | Zanthoxylum zanthoxyloides | |
| Geographical availability | Benin, Burkina, Gambia, Ghana, Guinea, Guinea-Bissau, Ivory Coast, Mali, Nigeria, Senegal, Togo | |
| Plant parts | Fruits | |
| Other cancers | Breast cancer, Liver cancer, Colon cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.42 mM against MCF-7 | |
| Potency | However, a weak cytotoxic activity was observed against breast cancer with an IC50 of 0.42 mM. | |
| Cell line/ mice model | WRL-68, CaCO2, MCF-7, PC-3 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:909846-1 | |
| Safety | NA |