Phytochemical Name : Yuanhuadine

Properties Information
PhytoCAT-ID PhytoCAT-1804
Phytochemical name or plant extracts Yuanhuadine
PMID 24059652
Literature evidence RESULTS: After confirmation of the anti-tumor activity, the 95% ethanolic extract was subjected to successive solvent partitioning to petroleum ether, dichloromethane, n-butanol, and water soluble fractions.
IUPAC name [(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-[(1E,3E)-nona-1,3-dienyl]-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] acetate
Phytochemicals’ class or type of plant extracts Diterpenoid
Source of phytochemicals or plant Extracts Daphne genkwa
Geographical availability China North-Central, China South-Central, China Southeast, Japan, Korea, Taiwan
Plant parts Dried flowers buds
Other cancers Breast cancer, Stomach cancer, Colorectal cancer, Lung cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 10 μg/mL against MCF-7 19 μg/mL against MDA-MB-231
Potency NA
Cell line/ mice model MCF-7, MDA-MB-231, Huh7, AGS, HT-29, B 16, Colo 205, A549, A2058
Additional information  NA
PubChem ID 6440572
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:831227-1
Safety NA