| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1800 | |
| Phytochemical name or plant extracts | Yuanhuacine | |
| PMID | 24059652 | |
| Literature evidence | RESULTS: After confirmation of the anti-tumor activity, the 95% ethanolic extract was subjected to successive solvent partitioning to petroleum ether, dichloromethane, n-butanol, and water soluble fractions. | |
| IUPAC name | [(1R,2R,6S,7S,8R,10S,11S,12R,14S,16S,17R,18R)-6,7-dihydroxy-8-(hydroxymethyl)-4,18-dimethyl-14-[(1E,3E)-nona-1,3-dienyl]-5-oxo-16-prop-1-en-2-yl-9,13,15,19-tetraoxahexacyclo[12.4.1.01,11.02,6.08,10.012,16]nonadec-3-en-17-yl] benzoate | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Daphne genkwa | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Korea, Taiwan | |
| Plant parts | Dried flowers buds | |
| Other cancers | Breast cancer, Stomach cancer, Colorectal cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 15 μg/mL against MCF-7 20 μg/mL against MDA-MB-231 | |
| Potency | Yuanhuacine was one of the compounds that exhibited potent cytotoxic activities. | |
| Cell line/ mice model | MCF-7, MDA-MB-231, Huh7, AGS, HT-29, B 16, Colo 205, A549, A2058 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:831227-1 | |
| Safety | NA |