Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-357 | |
Phytochemical name or plant extracts | Wightiic acid | |
PMID | 32278024 | |
Literature evidence | Antiproliferative activity of caged xanthones from the leaves of Garcinia wightii T. Anderson | |
IUPAC name | 2-{2-[(2S,17S,19S)-12-hydroxy-5-[hydroxy(3-hydroxy-3-methyloxiran-2-yl)methyl]-2,8,8,21,21-pentamethyl-14,18-dioxo-3,7,20-trioxapentacyclo[15.4.1.0²,¹⁵.0⁴,¹³.0⁶,¹¹]docosa-4(13),5,9,11,15-pentaen-19-yl]cycloprop-2-en-1-yl}acetic acid | |
Phytochemicals’ class or type of plant extracts | Xanthone | |
Source of phytochemicals or plant Extracts | Garcinia wightii | |
Geographical availability | India | |
Plant parts | Leaves | |
Other cancers | Breast cancer, Skin cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 5.2 μM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | MCF-7, SKBR-3, A-375 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:428318-1 | |
Safety | NA |