| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1630 | |
| Phytochemical name or plant extracts | Violaxanthin | |
| PMID | 21673891 | |
| Literature evidence | The potency to inhibit cell growth was used for the bio-guided fractionation and isolation of active compounds using chromatographic techniques. | |
| IUPAC name | (1R,3S,6S)-6-[(1E,3E,5E,7E,9E,11E,13E,15E,17E)-18-[(1S,4S,6R)-4-hydroxy-2,2,6-trimethyl-7-oxabicyclo[4.1.0]heptan-1-yl]-3,7,12,16-tetramethyloctadeca-1,3,5,7,9,11,13,15,17-nonaenyl]-1,5,5-trimethyl-7-oxabicyclo[4.1.0]heptan-3-ol | |
| Phytochemicals’ class or type of plant extracts | Carotenoid | |
| Source of phytochemicals or plant Extracts | Dunaliella tertiolecta | |
| Geographical availability | NA | |
| Plant parts | Green algae | |
| Other cancers | Breast cancer, Lung cancer, Prostate cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, MDA-MB-231, A549 , LNCaP | |
| Additional information | Taken together, our results demonstrate the strong antiproliferative activity of violaxanthin on one human mammary cancer cell line, and suggest that studying the pharmacology of violaxanthin and pharmacomodulated derivatives on cancer cells may allow potent antiproliferative drugs to be obtained. | |
| PubChem ID | 448438 | |
| Additional PMIDs | 20645919 21673891 15113052 | |
| Additional sources of information | NA | |
| Safety | NA |