Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1814 | |
Phytochemical name or plant extracts | Verticilla-4(20),7,11-triene | |
PMID | 24354175 | |
Literature evidence | Major constituents of Boswellia carteri resin exhibit cyclooxygenase enzyme inhibition and antiproliferative activity. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Boswellia carteri | |
Geographical availability | Oman, Somalia, Yemen | |
Plant parts | Gum | |
Other cancers | Breast cancer, Liver cancer | |
Target gene or protein | COX-1, COX-2 | |
Gene or Protein evidence | This is the first report of COX-1 and -2 enzyme and tumor cell proliferation inhibitory effects of compounds 1 and 2. | |
Target pathways | NA | |
IC50 | NA | |
Potency | NA | |
Cell line/ mice model | Hep-G2, MCF-7, RAW 264.7 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:127038-1 | |
Safety | NA |