| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-786 | |
| Phytochemical name or plant extracts | Uncaria tomentosa extract | |
| PMID | 11724307 | |
| Literature evidence | Extracts of the plant have been shown to possess cytostatic and anti-inflammatory activity as well as mutagenic and antimutagenic properties. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Uncaria tomentosa | |
| Geographical availability | Belize, Bolivia, Brazil North, Colombia, Costa Rica, Ecuador, French Guiana, Guatemala, Guyana, Honduras, Nicaragua, Panamá, Peru, Suriname, Trinidad-Tobago, Venezuela | |
| Plant parts | Barks and Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Two active fractions, which displayed an IC50 of 10 mg/ml and 20 mg/ml, respectively in MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Collectively, our findings provide compelling evidence indicating the therapeutic efficacy of U. tomentosa. Our data indicate that compounds in AEUt confer gastroprotection and that this preventive effect of AEUt was accompanied by gastric healing and a reduction in gastric ulcer recurrence. | |
| PubChem ID | NA | |
| Additional PMIDs | 26732910 38056537 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:768322-1 | |
| Safety | NA |