| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-592 | |
| Phytochemical name or plant extracts | Turraea robusta extract | |
| PMID | 26320684 | |
| Literature evidence | The antiplasmodial activities of the crude extracts and the isolated constituents against the D6 and W2 strains of Plasmodium falciparum were determined using the semiautomated micro dilution technique that measures the ability of the extracts to inhibit the incorporation of (G-(3)H, where G is guanine) hypoxanthine into the malaria parasite. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Turraea robusta | |
| Geographical availability | Cameroon, Kenya, Malawi, Tanzania, Uganda, Zambia, Zaïre | |
| Plant parts | Stem | |
| Other cancers | Breast cancer, Larynx cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Stem bark - 5.3±0.6 µg/mL against 4T1 | |
| Potency | The extracts showed good to moderate antiplasmodial activities, where the extract of the stem bark of T. robusta was also cytotoxic against the 4T1 and the HEp2 cells (IC50<10 μg/ml). | |
| Cell line/ mice model | 4T1, HEp2, Vero | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579836-1 | |
| Safety | NA |