| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-591 | |
| Phytochemical name or plant extracts | Turraea nilotica extract | |
| PMID | 26320684 | |
| Literature evidence | The antiplasmodial activities of the crude extracts and the isolated constituents against the D6 and W2 strains of Plasmodium falciparum were determined using the semiautomated micro dilution technique that measures the ability of the extracts to inhibit the incorporation of (G-(3)H, where G is guanine) hypoxanthine into the malaria parasite. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Turraea nilotica | |
| Geographical availability | Burundi, Ethiopia, Kenya, Malawi, Mozambique, Northern Provinces, Somalia, Sudan, Swaziland, Tanzania, Zambia, Zimbabwe | |
| Plant parts | Leaves, stem and root bark | |
| Other cancers | Breast cancer, Larynx cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Root bark - 18.6±1.2 µg/mL against 4T1. Leaves - 9.1±4.0 µg/mL against 4T1 | |
| Potency | The stem and root barks of T. nilotica also displayed considerable antiplasmodial activities (IC50<10 μg/ml) while its leaves showed only moderate activity. | |
| Cell line/ mice model | 4T1, HEp2, Vero | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:579805-1 | |
| Safety | NA |