Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1418 | |
Phytochemical name or plant extracts | Tupichinolide | |
PMID | 26610451 | |
Literature evidence | Compounds 1, 2, 5, and 6 showed significant cytotoxicity against six human cancer cell lines (HCT-116, HepG2, HeLa, SK-OV-3, and SK-MEL-5, and SK-BR-3). | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Monoterpenoid | |
Source of phytochemicals or plant Extracts | Adonis multiflora, Tupistra chinensis | |
Geographical availability | Japan, Korea China South-Central, China Southeast, Taiwan | |
Plant parts | Rhizome | |
Other cancers | Breast cancer, Colon cancer, Liver cancer, Lung cancer, Ovarian cancer, Skin cancer,Leukemia, Cervical cancer, Colorectal cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 2.58 ± 0.23 µM against SKBR-3 0.06 µM against MCF-7 | |
Potency | NA | |
Cell line/ mice model | HCT-116, HepG2, HeLa, SK-OV-3, SK-MEL-5, SKBR-3, HL-60, SMMC-7721,A-549,MCF-7,SW480 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | 22947328 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:936942-1 https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77214282-1 | |
Safety | NA |