Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1957 | |
Phytochemical name or plant extracts | Triregelin K | |
PMID | 28098763 | |
Literature evidence | The discovery of these twelve new diterpenes not only provided information on chemical substances of T. regelii, but also contributed to the chemical diversity of natural terpenoids. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Tripterygium regelii | |
Geographical availability | Japan, Korea, Manchuria | |
Plant parts | Stem | |
Other cancers | Breast cancer, Liver cancer, Ovarian cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 26.70 ± 5.57 µM against MCF-7 | |
Potency | Compound 11 showed solely cytotoxic effect on MCF-7 cell with an IC50 value of 26.70 µM. Compound 11 is Triregelin K | |
Cell line/ mice model | MCF-7, A2780, HepG2 | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:162907-1 | |
Safety | NA |