| Properties | Information |
|---|---|
| PhytoCAT-ID | PhytoCAT-1683 |
| Phytochemical name or plant extracts | Triphenylethylene-Coumarin Hybrid 5c |
| PMID | 30947677 |
| Literature evidence | Compound TCH-5c inhibited proliferation, resulted in cell death, increased p21 protein expression to induce G0/G1 arrest and changed endothelial cell cytoskeleton organization and migration in EA.hy926 endothelial cells. |
| IUPAC name | 3-phenyl-7-[2-(piperidin-1-yl)ethoxy]-4-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-2H-chromen-2-one |
| Phytochemicals’ class or type of plant extracts | Coumarin |
| Source of phytochemicals or plant Extracts | NA |
| Geographical availability | NA |
| Plant parts | NA |
| Other cancers | Breast cancer |
| Target gene or protein | NA |
| Gene or Protein evidence | NA |
| Target pathways | NA |
| IC50 | NA |
| Potency | Our results have potential implications in developing new approaches against breast cancer. |
| Cell line/ mice model | SKBR-3 |
| Additional information | Compound TCH-5c inhibited proliferation, resulted in cell death, increased p21 protein expression to induce G0/G1 arrest and changed endothelial cell cytoskeleton organization and migration in EA.hy926 endothelial cells. |
| PubChem ID | 71817959 |
| Additional PMIDs | NA |
| Additional sources of information | NA |
| Safety | NA |