| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-891 | |
| Phytochemical name or plant extracts | Trapa acornis husks (TAH) extract | |
| PMID | 32672134 | |
| Literature evidence | In conclusion, polyphenol-enriched extracts from TAH might inhibit breast cancer cell proliferation and In Vivo tumor angiogenesis. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Polyphenol-enriched extract | |
| Source of phytochemicals or plant Extracts | Trapa acornis | |
| Geographical availability | Assam, China North-Central, China South-Central, China Southeast, Hainan, Japan, Nepal, Primorye, Thailand, West Himalaya | |
| Plant parts | Husk | |
| Other cancers | Breast cancer | |
| Target gene or protein | VEGF, p-Her2, p-ERK1/2, VEGF, MMP2, MMP9, uPA | |
| Gene or Protein evidence | The mRNA expression levels of VEGF, MMP2, MMP9, and uPA were reduced after TAH extracts intervention (P < 0.01). TAH extracts also decreased the protein expression of p-Her2, p-ERK1/2, VEGF, MMP2, MMP9, and uPA (P < 0.01). | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | NA | |
| Cell line/ mice model | Female BALB/C-nu mice, SKBR-3 | |
| Additional information | In conclusion, polyphenol-enriched extracts from TAH might inhibit breast cancer cell proliferation and In Vivo tumor angiogenesis. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:836114-1 | |
| Safety | NA |