| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1197 | |
| Phytochemical name or plant extracts | Tragopogon porrifolius extract | |
| PMID | 31879598 | |
| Literature evidence | The antioxidant activity evaluated using the DPPH radical scavenging, thiobarbituric acid and reducing power methods. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Tragopogon porrifolius | |
| Geographical availability | Albania, Algeria, Baleares, Baltic States, Bulgaria, Canary Is., Corse, Czechoslovakia, East Aegean Is., France, Great Britain, Greece, Italy, Kriti, Libya, Morocco, Portugal, Romania, Sardegna, Saudi Arabia, Sicilia, Spain, Tunisia, Turkey, Turkey-in-Europe, Ukraine, West Himalaya, Yugoslavia | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | CAT | |
| Gene or Protein evidence | Also, in the CCl4-treated groups (VI, VII, and VIII), the extract raised the CAT levels by 72, 124, and 222%, respectively, compared to the control group. | |
| Target pathways | NA | |
| IC50 | 0.0625 mg/mL against MDA-MB-231 | |
| Potency | Both extracts also exhibited significant anticancer effect on MDA-MB-231 breast cancer cells. | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | T. porrifolius exhibited higher α-glucosidase inhibitory activity, and both extract showed strong α-amylase inhibition activity compared to reference drug acarbose. T. porrifolius and P. cognatum ethanolic extracts exhibited antimicrobial activity in the concentration range of 0.039-2.5 mg/ml. | |
| PubChem ID | NA | |
| Additional PMIDs | 25694787 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:256109-1 | |
| Safety | NA |