| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-419 | |
| Phytochemical name or plant extracts | Thymus vulgaris L. essential oil | |
| PMID | 34162964 | |
| Literature evidence | Among natural products, essential oils from aromatic plants have been reported to possess potent anticancer properties. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil | |
| Source of phytochemicals or plant Extracts | Thymus vulgaris | |
| Geographical availability | Baleares, France, Italy, Spain | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Lung cancer, Leukemia | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 52.65 μg/mL against MCF-7 | |
| Potency | Essential oil induced a dose-dependent inhibition of cell proliferation in all tested tumor cell lines and showed different sensitivity. | |
| Cell line/ mice model | MCF-7, NCI-H460, MOLT-4 | |
| Additional information | Dose dependent toxicity observed in bioassay as well as the in vitro assay confirmed that brine shrimp lethality test is an adequate method for preliminary toxicity testing of Thymus vulgaris L. essential oil in tumor cell lines. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:461765-1 | |
| Safety | NA |