| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1825 | |
| Phytochemical name or plant extracts | Thymus caramanicus extract (TCE) | |
| PMID | 24812569 | |
| Literature evidence | In conclusion, thymus extract has a potential proapoptotic/antiproliferative property against human breast cancer cells and its combination with chemotherapeutic agent vincristine may induce cell death effectively and be a potent modality to treat this type of cancer. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Thymus caramanicus Jalas | |
| Geographical availability | Iran, Iraq | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Taken together, this study indicates that T. caramanicus extract has a potential antiproliferative/proapoptotic property in MCF-7 cells and can be used as pharmaceutic case study for breast cancer treatments. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | In traditional folk medicine, leaves of this plant are used in the treatment of rheumatism and skin disorders and as an antibacterial agent. TCE induced cell toxicity is performed through the induction of apoptosis and inhibition of cell proliferation | |
| PubChem ID | NA | |
| Additional PMIDs | 28301021 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:901144-1 | |
| Safety | NA |