| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-536 | |
| Phytochemical name or plant extracts | Thiosulfinates | |
| PMID | 17711341 | |
| Literature evidence | These results suggest that thiosulfinates from Allium tuberosum L. inhibit the proliferation of cancer cells via apoptosis and have antitumor activities. | |
| IUPAC name | (E)-1-[(E)-prop-1-enyl]sulfinylsulfanylprop-1-ene | |
| Phytochemicals’ class or type of plant extracts | Organosulfur | |
| Source of phytochemicals or plant Extracts | Allium tuberosum | |
| Geographical availability | Assam, China North-Central, Nepal, West Himalaya | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Liver cancer, Prostate cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 14.23 ± 0.72 µg/mL against MCF-7 | |
| Potency | The crude thiosulfinates also induced apoptosis in MCF-7 cancer cells. These results suggest that thiosulfinates from Allium tuberosum L. inhibit the proliferation of cancer cells via apoptosis and have antitumor activities. | |
| Cell line/ mice model | MCF-7, SW480, HepG2, LNCaP.FGC, mice | |
| Additional information | NA | |
| PubChem ID | 58219327 | |
| Additional PMIDs | 28858299 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:529062-1 | |
| Safety | NA |