Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-839 | |
Phytochemical name or plant extracts | Terpecurcumin Q | |
PMID | 24219305 | |
Literature evidence | Finally, LC/MS/MS quantitative analysis of five representative terpecurcumins indicated these novel compounds were present in C. longa at parts per million level. | |
IUPAC name | (1E,6E)-4-[4,8-dimethyl-6-(2-methylprop-1-enyl)-2-bicyclo[3.3.1]non-3-enyl]-1,7-bis(4-hydroxy-3-methoxyphenyl)hepta-1,6-diene-3,5-dione | |
Phytochemicals’ class or type of plant extracts | Terpene-conjugated curcuminoids | |
Source of phytochemicals or plant Extracts | Curcuma longa | |
Geographical availability | India | |
Plant parts | Rhizome | |
Other cancers | Breast cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | Mitochondria-mediated apoptosis | |
IC50 | 3.9 μM against MCF-7 | |
Potency | Among them, terpecurcumin Q (8) exhibited IC50 of 3.9 μM against MCF-7 human breast cancer cells, and mitochondria-mediated apoptosis played an important role in the overall growth inhibition. | |
Cell line/ mice model | MCF-7 | |
Additional information | NA | |
PubChem ID | 102230692 | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:796451-1 | |
Safety | NA |