| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-310 | |
| Phytochemical name or plant extracts | Terminamines S | |
| PMID | 27681716 | |
| Literature evidence | In addition, the isolates were examined for their ability to inhibit the migration of MDA-MB-231 cells induced by the chemokine epidermal growth factor (EGF). | |
| IUPAC name | (3S,8R,9S,10R,13S,14S,17Z)-3-(dimethylamino)-17-ethylidene-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15-decahydro-1H-cyclopenta[a]phenanthren-16-one | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Pachysandra terminalis | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Sakhalin | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.01 ± 0.09 μM against MDA-MB-231 | |
| Potency | Alkaloids 1, 5, 7, 9, 12, and 17 presented significant anti-metastasis activities compared with the positive reagent, LY294002. Compound 9 is Terminamines S | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | NA | |
| PubChem ID | 132508274 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:353208-1 | |
| Safety | NA |