| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-308 | |
| Phytochemical name or plant extracts | Terminamines Q | |
| PMID | 27681716 | |
| Literature evidence | In addition, the isolates were examined for their ability to inhibit the migration of MDA-MB-231 cells induced by the chemokine epidermal growth factor (EGF). | |
| IUPAC name | N-[(3S,8S,9S,10R,13S,14S,16S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-16-hydroxy-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-yl]-3-methylbut-2-enamide | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Pachysandra terminalis | |
| Geographical availability | China North-Central, China South-Central, China Southeast, Japan, Sakhalin | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 1.38 ± 0.17 μM against MDA-MB-231 | |
| Potency | Alkaloids 1, 5, 7, 9, 12, and 17 presented significant anti-metastasis activities compared with the positive reagent, LY294002. Compound 7 is Terminamines Q | |
| Cell line/ mice model | MDA-MB-231 | |
| Additional information | NA | |
| PubChem ID | 132508272 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:353208-1 | |
| Safety | NA |