Phytochemical Name : Terminamines L

Properties Information
PhytoCAT-ID PhytoCAT-303
Phytochemical name or plant extracts Terminamines L
PMID 27681716
Literature evidence In addition, the isolates were examined for their ability to inhibit the migration of MDA-MB-231 cells induced by the chemokine epidermal growth factor (EGF).
IUPAC name 1-[(3S,5R,8S,9S,10R,13S,14S,17S)-17-[(1S)-1-(dimethylamino)ethyl]-10,13-dimethyl-4-oxo-1,2,3,5,6,7,8,9,11,12,14,15,16,17-tetradecahydrocyclopenta[a]phenanthren-3-yl]-3-propan-2-ylideneazetidin-2-one
Phytochemicals’ class or type of plant extracts Alkaloid
Source of phytochemicals or plant Extracts Pachysandra terminalis
Geographical availability China North-Central, China South-Central, China Southeast, Japan, Sakhalin
Plant parts Whole plant
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 4.65 ± 0.82 μM against MDA-MB-231
Potency NA
Cell line/ mice model MDA-MB-231
Additional information  NA
PubChem ID 132508267
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:353208-1
Safety NA