| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1915 | |
| Phytochemical name or plant extracts | Tengechlorenine | |
| PMID | 28926237 | |
| Literature evidence | Compound (+)-1 displayed a selective in vitro cytotoxic effect against MDA-MB-468 cells (IC50 7.4 μM), while compound 2 showed pronounced in vitro cytotoxic activity against all three breast cancer cell lines tested (MDA-MB-468, MDA-MB-231, and MCF7, IC50 values of 0.038-0.91 μM). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Alkaloid | |
| Source of phytochemicals or plant Extracts | Ficus fistulosa | |
| Geographical availability | Andaman Is., Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, New Guinea, Nicobar Is., Philippines, Sulawesi, Sumatera, Taiwan, Thailand, Vietnam | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 0.038 μM against MDA-MB-468, 0.48 ± 0.05 μM against MDA-MB-231, 0.91 ± 0.06 μM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MDA-MB-468, MDA-MB-231, and MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:852846-1 | |
| Safety | NA |