| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1931 | |
| Phytochemical name or plant extracts | Tebesinone B | |
| PMID | 29772301 | |
| Literature evidence | The cytotoxic activities of the crude extracts and isolated compounds were evaluated against MCF-7, B16F10, PC-3 and C26 human cancer cell lines, in which compounds 2 and 3 showed significant cytotoxic activities (IC50 2.1-10.3 μM). | |
| IUPAC name | 2-(1-hydroxypropan-2-yl)-8,8-dimethyl-1,4,5,6,7,8-hexahydroanthracene-1,4-dione | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Salvia tebesana Bunge | |
| Geographical availability | Afghanistan, Iran, Pakistan | |
| Plant parts | Root | |
| Other cancers | Breast cancer , Skin cancer, Prostate cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 7.56 ± 0.82 μM against MCF-7 | |
| Potency | Shows significant cytotoxic activities against MCF-7, B16F10, PC-3 and C26 human cancer cell lines | |
| Cell line/ mice model | MCF-7, B16F10, PC-3, C26 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:457368-1 | |
| Safety | NA |