| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-997 | |
| Phytochemical name or plant extracts | Tanacetum Polycephalum extract (TPHE) | |
| PMID | 24995928 | |
| Literature evidence | High content screening was applied to analyze the cell membrane permeability, nuclear condensation, mitochondrial membrane potential (MMP) and cytochrome c release. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hexane extract | |
| Source of phytochemicals or plant Extracts | Tanacetum polycephalum | |
| Geographical availability | Transcaucasus, Turkey | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | Taken together, the results presented in this study demonstrated that the hexane extract of T. Polycephalum inhibits the proliferation of MCF7 cells, resulting in the cell cycle arrest and apoptosis, which was explained to be through the mitochondrial pathway. | |
| IC50 | 6.42±0.35 µg/mL against MCF-7 | |
| Potency | Overall, this study demonstrates the potential applications of VA as an anti-cancer drug for breast cancer treatment. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:952514-1 | |
| Safety | NA |