| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1192 | |
| Phytochemical name or plant extracts | Tamarix aphylla essential oil | |
| PMID | 30034503 | |
| Literature evidence | In vitro screening of potential cytotoxicity of the aqueous (AE) and ethanol (EE) extracts was also evaluated against human breast adenocarcinoma (MCF-7), colorectal adenocarcinoma (Caco-2), and pancreatic carcinoma (Panc-1) cancer cell lines as well as normal human fibroblasts. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Essential oil, Aqueous extract, Ethanolic extract | |
| Source of phytochemicals or plant Extracts | Tamarix aphylla | |
| Geographical availability | Afghanistan, Algeria, Chad, Djibouti, Egypt, Eritrea, Ethiopia, Gulf States, India, Iran, Iraq, Kenya, Kuwait, Libya, Mauritania, Morocco, Niger, Oman, Pakistan, Palestine, Saudi Arabia, Senegal, Sinai, Socotra, Somalia, Sudan, Tunisia, Yemen | |
| Plant parts | Aerial parts | |
| Other cancers | Breast cancer, Colorectal cancer, Pancreatic cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | Aqueous extract - 2.17 ± 0.10 μg/mL against MCF-7 Ethanol extract - 26.65 ± 3.09 μg/mL against MCF-7 | |
| Potency | The data obtained in this study suggest that diferent extracts of T. aphylla have potential antiproliferative activities against MCF-7 cancer cell line, which could be a source of promising lead compounds for the development of new treatments for some cancer types. | |
| Cell line/ mice model | MCF-7, Caco-2, Panc-1 | |
| Additional information | In Saudi Arabia, alcohol extract from leaves of T. aphylla was shown to possess antioxidant, anti-inflammatory, and wound-healing activities. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:828051-1 | |
| Safety | NA |