| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1191 | |
| Phytochemical name or plant extracts | Tagetone A | |
| PMID | 28807229 | |
| Literature evidence | Compound 1 showed cytotoxic activity towards MCF7 and A549 cancer cells with IC50 values being 4.68 and 4.24 µmol·L-1, respectively, compared to doxorubicin (IC50 0.13 and 1.12 µmol·L-1, respectively). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Tagetes minuta | |
| Geographical availability | Argentina Northeast, Argentina Northwest, Bolivia, Brazil Northeast, Brazil South, Brazil Southeast, Brazil West-Central, Chile Central, Chile North, Paraguay, Uruguay | |
| Plant parts | Flowers | |
| Other cancers | Breast cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 4.68 µmol/L against MCF-7 | |
| Potency | Compound 1 showed cytotoxic activity towards MCF7 and A549 cancer cells with IC50 values being 4.68 and 4.24 µmol·L-1, respectively, compared to doxorubicin (IC50 0.13 and 1.12 µmol·L-1, respectively). | |
| Cell line/ mice model | MCF-7 and A549 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:252132-1 | |
| Safety | NA |