| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-635 | |
| Phytochemical name or plant extracts | Syzygium aromaticum extract (SA-EXT) | |
| PMID | 33867344 | |
| Literature evidence | Volatile constituents and in vitro activity of Syzygium aromaticum flower buds (clove) against human cancer cell lines | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Methanolic extract | |
| Source of phytochemicals or plant Extracts | Syzygium aromaticum | |
| Geographical availability | Maluku | |
| Plant parts | Cloves | |
| Other cancers | Breast cancer, Cervical cancer, Lung cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | GI50: 36 μg/ml against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | MCF-7, HeLa, NCI-H-460 | |
| Additional information | The most active sub-fraction (SA-PES-Fr-2) analyzed by GC and GC-MS techniques revealed that eugenol was most abundant (85.34%) along with minor constituents. Thus it can be concluded that growth inhibitory and cytotoxic effect residing in Syzygium aromaticum flower buds (clove) is more likely due to eugenol. | |
| PubChem ID | NA | |
| Additional PMIDs | 25075040 25276075 33568035 28358602 22292639 30210543 32099733 33867344 28110253 23144548 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:601421-1 | |
| Safety | LC50=86 ± 2.8 μg/mL against MCF-7 |