Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1239 | |
Phytochemical name or plant extracts | Sugiol | |
PMID | 29451710 | |
Literature evidence | The individual compounds (1, 3 - 8) were screened for cytotoxic activity, using the sulforhodamine B bioassay (SRB) method. | |
IUPAC name | (4aS,10aS)-6-hydroxy-1,1,4a-trimethyl-7-propan-2-yl-3,4,10,10a-tetrahydro-2H-phenanthren-9-one | |
Phytochemicals’ class or type of plant extracts | Diterpenoid | |
Source of phytochemicals or plant Extracts | Salvia deserta | |
Geographical availability | Altay, Kazakhstan, Kirgizstan, Tadzhikistan, Uzbekistan, West Siberia, Xinjiang | |
Plant parts | Root | |
Other cancers | Breast cancer, Lung cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | >40 µM against MDA-MB-231, MCF-7 | |
Potency | NA | |
Cell line/ mice model | A549, MDA-MB-231, KB, KB-VIN, and MCF-7 | |
Additional information | NA | |
PubChem ID | 94162 | |
Additional PMIDs | 33673350 29451710 30840453 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:456094-1 | |
Safety | NA |