| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-65 | |
| Phytochemical name or plant extracts | Styrylpyrone dehydrogoniothalamin | |
| PMID | 33477019 | |
| Literature evidence | Overall, these findings showed compound 3 to be a promising prototype against TNBC cells that tend to respond poorly to conventional therapies. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Styrylpyrone | |
| Source of phytochemicals or plant Extracts | Aniba heringeri | |
| Geographical availability | Brazil North, Brazil Northeast, Brazil Southeast, Brazil West-Central | |
| Plant parts | Leaves | |
| Other cancers | Breast cancer, Prostate cancer, Kidney cancer, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Compound 1 inhibited cell growth by 50% (GI50) at concentrations in the 90.4-175.7 μM range, while 2 proved active against MCF-7 and MDA-MB-231 breast cells (GI50 = 12.24, and 34.22 μM, respectively). | |
| Cell line/ mice model | PC-3, 786-0, HT-29, MCF-7, MDA-MB-231 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:13840-2 | |
| Safety | NA |