| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-575 | |
| Phytochemical name or plant extracts | Strobilanthes crispa extract | |
| PMID | 29085507 | |
| Literature evidence | Therefore, recent research has been focused on identifying alternative therapeutic agents extracted from plant-based sources in order to develop novel treatment options for cancer. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Hexane extract | |
| Source of phytochemicals or plant Extracts | Strobilanthes crispa | |
| Geographical availability | Jawa, Lesser Sunda Is. | |
| Plant parts | Stem | |
| Other cancers | Breast cancer | |
| Target gene or protein | Caspase 8 | |
| Gene or Protein evidence | Furthermore, it altered cell cycle profile and significantly increased caspase-8 activity in HepG-2 cells, but not in MDA-MB-231 cells. | |
| Target pathways | NA | |
| IC50 | 42.50±39.67 μg/mL against MDA-MB-231 | |
| Potency | NA | |
| Cell line/ mice model | HepG-2, MDA-MB-231 | |
| Additional information | Among the extracts tested, SH extract exhibited the lowest half maximal inhibitory concentrations in both the cell lines. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:55623-1 | |
| Safety | NA |