Phytochemical Name : Sterigmatocystin

Properties Information
PhytoCAT-ID PhytoCAT-2074
Phytochemical name or plant extracts Sterigmatocystin
PMID 30152287
Literature evidence The study shows that fungus Aspergillus nidulans from Nyctanthes arbor-tristis is capable of producing biologically active natural compounds and provides a scientific rationale for further chemical investigations of endophyte-producing natural products.
IUPAC name NA
Phytochemicals’ class or type of plant extracts Organic heteropentacyclic compound
Source of phytochemicals or plant Extracts Endophytic fungus Aspergillus nidulans, associated with Nyctanthes arbor-tristisinn.
Geographical availability Assam, Bangladesh, Cambodia, East Himalaya, India, Jawa, Laos, Nepal, Sumatera, Thailand, Vietnam
Plant parts Mycelium
Other cancers Breast cancer, Lung cancer, Cervical cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 50 ± 2.5 µM/mL µg/mL against MCF-7
Potency Sterigmatocystin exhibited growth inhibitory effect (IC50 = 50 ± 2.5 µM/mL) against only MCF-7 cell line whereas other compounds had IC50 > 100.
Cell line/ mice model MCF-7, NCI-H460, HeLa
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:610599-1
Safety NA