Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-2074 | |
Phytochemical name or plant extracts | Sterigmatocystin | |
PMID | 30152287 | |
Literature evidence | The study shows that fungus Aspergillus nidulans from Nyctanthes arbor-tristis is capable of producing biologically active natural compounds and provides a scientific rationale for further chemical investigations of endophyte-producing natural products. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Organic heteropentacyclic compound | |
Source of phytochemicals or plant Extracts | Endophytic fungus Aspergillus nidulans, associated with Nyctanthes arbor-tristisinn. | |
Geographical availability | Assam, Bangladesh, Cambodia, East Himalaya, India, Jawa, Laos, Nepal, Sumatera, Thailand, Vietnam | |
Plant parts | Mycelium | |
Other cancers | Breast cancer, Lung cancer, Cervical cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 50 ± 2.5 µM/mL µg/mL against MCF-7 | |
Potency | Sterigmatocystin exhibited growth inhibitory effect (IC50 = 50 ± 2.5 µM/mL) against only MCF-7 cell line whereas other compounds had IC50 > 100. | |
Cell line/ mice model | MCF-7, NCI-H460, HeLa | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:610599-1 | |
Safety | NA |