| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-516 | |
| Phytochemical name or plant extracts | Sophopterocarpan A | |
| PMID | 28654120 | |
| Literature evidence | Additionally, it was found that 1 exhibited cytotoxic activity in MCF-7 cells with an IC50 of 29.36 μM. | |
| IUPAC name | (1R,2R,10R,11R,16R)-1,11,16-trihydroxy-6-methoxy-3-oxatetracyclo[10.3.1.02,10.04,9]hexadeca-4(9),5,7,14-tetraen-13-one | |
| Phytochemicals’ class or type of plant extracts | Flavonoid | |
| Source of phytochemicals or plant Extracts | Sophora flavescens | |
| Geographical availability | Altay, Amur, China North-Central, China South-Central, China Southeast, Chita, Hainan, Inner Mongolia, Irkutsk, Japan, Khabarovsk, Korea, Manchuria, Mongolia, Primorye, Qinghai, Taiwan, Tibet, Xinjiang | |
| Plant parts | Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 29.36 μM against MCF-7 | |
| Potency | Sophopterocarpan A was identified as a potential autophagy activator. Additionally, it was found that 1 exhibited cytotoxic activity in MCF-7 cells with an IC50 of 29.36 μM. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | NA | |
| PubChem ID | 132610051 | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:518831-1 | |
| Safety | NA |