Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1866 | |
Phytochemical name or plant extracts | Solanum torvum extract | |
PMID | 26415618 | |
Literature evidence | Methyl caffeate significantly reduced cell proliferation and increased formation of fragmented DNA and apoptotic body in MCF-7 cells. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Ethyl acetate extract | |
Source of phytochemicals or plant Extracts | Solanum torvum | |
Geographical availability | Bolivia, Brazil North, Brazil Northeast, Brazil Southeast, Colombia, Ecuador, French Guiana, Guyana, Nicaragua, Panamá, Peru, Suriname, Trinidad-Tobago, Venezuela | |
Plant parts | Fruits | |
Other cancers | Breast cancer, Lung cancer, Liver cancer, Colon cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 3 mg/mL for 24h against MCF-7 | |
Potency | Ethyl acetate extract showed good cytotoxic properties in vitro against MCF-7 cells at 3 mg/mL (IC50) when compared to hexane and methanol extracts | |
Cell line/ mice model | MCF-7, A549, COLO320, HepG-2, Vero | |
Additional information | NA | |
PubChem ID | NA | |
Additional PMIDs | 34643844 34643844 32608263 33813958 34757509 | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:821288-1 | |
Safety | NA |