Phytochemical Name : Sinopodophylliside A

Properties Information
PhytoCAT-ID PhytoCAT-2151
Phytochemical name or plant extracts Sinopodophylliside A
PMID 28411691
Literature evidence Compounds 1-6, 9-11, and 14-17 were tested for their cytotoxicity against human breast-cancer T47D, MCF-7 and MDA-MB-231 cells in vitro, and compounds 2, 5, 6, 10 and 11 showed significant cytotoxicity (IC50 values < 10 μmol·L-1) against T47D cells.
IUPAC name tricetin-3′-O-βD-glucopyranoside-7-methyl ether
Phytochemicals’ class or type of plant extracts Flavonoid glycoside
Source of phytochemicals or plant Extracts Sinopodophyllum hexandrum
Geographical availability Afghanistan, China North-Central, China South-Central, East Himalaya, Nepal, Pakistan, Qinghai, Tibet, West Himalaya
Plant parts Fruits
Other cancers Breast cancer
Target gene or protein NA
Gene or Protein evidence NA
Target pathways NA
IC50 89.5 ± 3.20 μmol/L against MCF-7 66.3 ± 2.03 μmol/L against MDA-MB-231
Potency NA
Cell line/ mice model MCF-7, MDA-MB-231, T47D
Additional information  NA
PubChem ID NA
Additional PMIDs NA
Additional sources of information https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77137821-1
Safety NA