| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-722 | |
| Phytochemical name or plant extracts | Sinchiangensine A | |
| PMID | 28074665 | |
| Literature evidence | Additionally, sinchiangensine A and its known analogue 3 were first reported as potential antitumor and antibacterial diterpenoid alkaloids, which showed significant antitumor activities against tumour cells (HL-60, A-549, SMCC-7721, MCF-7 and SW480), with IC50 comparable to cisplatin, and significant antibacterial activities against Staphylococcus aureus ATCC-25923 with MIC value of 0.147 and 0.144 μmol/mL, respectively. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid alkaloid | |
| Source of phytochemicals or plant Extracts | Aconitum sinchiangense | |
| Geographical availability | Xinjiang | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Lung cancer, Leukemia, Liver cancer, Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Compound 1–3 showed strong antibacterial activity against E. coli ATCC-25922 with MIC value of 0.142, 0.289 and 0.144 μmol/mL, respectively. | |
| Cell line/ mice model | HL-60, A-549, SMCC-7721, MCF-7 and SW480 cell line. | |
| Additional information | IC50 comparable to cisplatin, and significant antibacterial activities against Staphylococcus aureus ATCC-25923 with MIC value of 0.147 and 0.144 μmol/mL, respectively. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:707820-1 | |
| Safety | NA |