| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-694 | |
| Phytochemical name or plant extracts | Sinapinic acid | |
| PMID | 27588384 | |
| Literature evidence | The purpose of this study was to evaluate the antiproliferative and histone deacetylase (HDAC) inhibitory activity of selected peanut phenolics, including p-coumaric acid, ferulic acid, sinapinic acid and resveratrol, in MCF-7 and HeLa cells. | |
| IUPAC name | (E)-3-(4-hydroxy-3,5-dimethoxyphenyl)prop-2-enoic acid | |
| Phytochemicals’ class or type of plant extracts | Phenolic acid | |
| Source of phytochemicals or plant Extracts | Limoniastrum guyonianum | |
| Geographical availability | Algeria, Egypt, Libya, Tunisia | |
| Plant parts | NA | |
| Other cancers | Breast cancer, Cervical cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | Sinapinic acid denitrosate RSNO and does not reduce disulfides. Thus can readily replace ascorbate in detection of S-nitrosated proteins in biotin switch assay. | |
| Cell line/ mice model | MCF-7, HeLa | |
| Additional information | Sinapic acid inhibits pancreatic cancer proliferation, migration, and invasion via downregulation of the AKT/Gsk-3β signal pathway. | |
| PubChem ID | 637775 | |
| Additional PMIDs | 34859906 19837133 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:686606-1 DrugBank Accession Number DB08587 | |
| Safety | NA |