| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-2084 | |
| Phytochemical name or plant extracts | Selaginella repanda extract | |
| PMID | 33540783 | |
| Literature evidence | S. repanda, which is a rich source of potent natural bioactive compounds, showed promising antibacterial activity against the tested pathogenic bacteria (S. aureus, P. aeruginosa, E. coli and S. flexneri). | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Ethanolic crude extract | |
| Source of phytochemicals or plant Extracts | Selaginella repanda | |
| Geographical availability | Assam, Bangladesh, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Nepal, Philippines, Sumatera, Taiwan, Thailand, Vietnam, West Himalaya | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Lung cancer , Colorectal cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 428.3 μg/mL against MCF-7 | |
| Potency | Higher activity was found against lung (A549) (IC50 = 341.1 μg/mL), followed by colon (HCT-116) (IC50 = 378.8 μg/mL) and breast (MCF-7) (IC50 = 428.3 μg/mL) cancer cells. | |
| Cell line/ mice model | A549, HCT-116, MCF-7 | |
| Additional information | S. repanda, which is a rich source of potent natural bioactive compounds, showed promising antibacterial activity against the tested pathogenic bacteria (S. aureus, P. aeruginosa, E. coli and S. flexneri). The crude extract displayed favorable antioxidant activity against both 2,2-diphenyl-1-picrylhydrazyl (DPPH) (IC50 = 231.6 μg/mL) and H2O2 (IC50 = 288.3 μg/mL) molecules. S. repanda also showed favorable and effective anticancer activity against all three malignant cancer cells in a dose/time dependent manner. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:77186632-1 | |
| Safety | NA |