| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-333 | |
| Phytochemical name or plant extracts | Secofriedelanophyllemblicine | |
| PMID | 34514922 | |
| Literature evidence | Further flow cytometric analysis showed that secofriedelanophyllemblicine could inhibit cell proliferation and induced G2 phase arrest in the cell-cycle progression of MCF-7 cells. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Triterpenoid | |
| Source of phytochemicals or plant Extracts | Phyllanthus emblica | |
| Geographical availability | Assam, Bangladesh, Borneo, Cambodia, China South-Central, China Southeast, East Himalaya, Hainan, India, Jawa, Laos, Lesser Sunda Is., Malaya, Myanmar, Pakistan, Sri Lanka, Sumatera, Taiwan, Thailand, Vietnam, West Himalaya | |
| Plant parts | Root | |
| Other cancers | Breast cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | NA | |
| Potency | The gathered results suggest that secofriedelanophyllemblicine is a cell-cycle regulator in MCF-7 human breast cancer cells and might be used as a candidate chemopreventive agent for breast cancer prevention and intervention. | |
| Cell line/ mice model | MCF-7 | |
| Additional information | Secofriedelanophyllemblicine exhibited cell growth inhibition specifically on MCF-7 breast cancer cells when compared to other tested cell lines. | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:353838-1 | |
| Safety | NA |