| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1253 | |
| Phytochemical name or plant extracts | Scutestrigillosins C | |
| PMID | 26920801 | |
| Literature evidence | In vitro, the isolated three new compounds exhibited significant cytotoxic activities against four tumor cell lines (HONE-1, P-388, MCF7 and HT29), and gave IC50 values in the range 3.5-7.7μM. | |
| IUPAC name | (1R,2S,3R,4R,4aS,8aR)-3-hydroxy-2-[(2-hydroxy-3-methylbutanoyl)oxy]-3,4,8,8a-tetramethyl-4-[(1E)-2-(5-oxo-2,5-dihydrofuran-3-yl)ethenyl]-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yl benzoate | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Scutellaria strigillosa | |
| Geographical availability | China North-Central, China Southeast, Japan, Khabarovsk, Korea, Kuril Is., Manchuria, Primorye, Sakhalin | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Epithelial cancer, Leukemia, Colon cancer | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 5.2±1.4 µM against MCF-7 | |
| Potency | NA | |
| Cell line/ mice model | HONE-1, P-388, MCF-7 and HT29 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458682-1 | |
| Safety | NA |