| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-1251 | |
| Phytochemical name or plant extracts | Scutestrigillosins A | |
| PMID | 26920801 | |
| Literature evidence | In vitro, the isolated three new compounds exhibited significant cytotoxic activities against four tumor cell lines (HONE-1, P-388, MCF7 and HT29), and gave IC50 values in the range 3.5-7.7μM. | |
| IUPAC name | (1S,3R,5R,6R,6aR,10aR)-6a,7-dimethyl-5'-oxo-5-[(1-phenylethenyl)oxy]-1-(pyridine-3-carbonyloxy)-1,2,4a,5,6,6a,9,10,10a,10b-decahydrospiro[naphtho[2,1-b]pyran-3,3'-oxolan]-6-yl pyridine-3-carboxylate | |
| Phytochemicals’ class or type of plant extracts | Diterpenoid | |
| Source of phytochemicals or plant Extracts | Scutellaria strigillosa | |
| Geographical availability | China North-Central, China Southeast, Japan, Khabarovsk, Korea, Kuril Is., Manchuria, Primorye, Sakhalin | |
| Plant parts | Whole plant | |
| Other cancers | Breast cancer, Epithelial cancer, Colon cancer, Lymphoma | |
| Target gene or protein | NA | |
| Gene or Protein evidence | NA | |
| Target pathways | NA | |
| IC50 | 5.7±1.8 µM against MCF-7 | |
| Potency | In vitro, the isolated three new compounds exhibited significant cytotoxic activities against four tumor cell lines (HONE-1, P-388, MCF7 and HT29), and gave IC50 values in the range 3.5-7.7?M. | |
| Cell line/ mice model | HONE-1, P-388, MCF-7 and HT29 | |
| Additional information | NA | |
| PubChem ID | NA | |
| Additional PMIDs | NA | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458682-1 | |
| Safety | NA |