Properties | Information | |
---|---|---|
PhytoCAT-ID | PhytoCAT-1733 | |
Phytochemical name or plant extracts | Scutellaria litwinowii extract | |
PMID | 20028719 | |
Literature evidence | Scutellaria litwinowii exerts cytotoxic and proapototic effects in a variety of malignant cell lines and could be considered as a potential chemotherapeutic agent in cancer treatment. | |
IUPAC name | NA | |
Phytochemicals’ class or type of plant extracts | Methylene chloride fraction | |
Source of phytochemicals or plant Extracts | Scutellaria litwinowii | |
Geographical availability | Afghanistan, Iran, Turkmenistan | |
Plant parts | Root | |
Other cancers | Breast cancer, Cervical cancer, AdKidney cancer | |
Target gene or protein | NA | |
Gene or Protein evidence | NA | |
Target pathways | NA | |
IC50 | 115.9 ± 3.5 μg/ml against MCF-7 | |
Potency | Scutellaria litwinowii exerts cytotoxic and proapototic effects in a variety of malignant cell lines and could be considered as a potential chemotherapeutic agent in cancer treatment. | |
Cell line/ mice model | AGS, HeLa, MCF-7, PC12 and NIH 3T3 | |
Additional information | Taking together, this study showed that S. litwinowii inhibits the proliferation of a variety of malignant cell lines with the involvement of apoptosis or programmed cell death. | |
PubChem ID | NA | |
Additional PMIDs | NA | |
Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458423-1 | |
Safety | NA |