| Properties | Information | |
|---|---|---|
| PhytoCAT-ID | PhytoCAT-415 | |
| Phytochemical name or plant extracts | Scutellaria baicalensis extract | |
| PMID | 12470437 | |
| Literature evidence | This study supports the notion of using Scutellaria baicalensis as a novel anticancer agent to treat various cancers. | |
| IUPAC name | NA | |
| Phytochemicals’ class or type of plant extracts | Extract | |
| Source of phytochemicals or plant Extracts | Scutellaria baicalensis | |
| Geographical availability | Amur, Buryatiya, China North-Central, China South-Central, Chita, Inner Mongolia, Irkutsk, Khabarovsk, Korea, Manchuria, Mongolia, Primorye, Vietnam, Yakutskiya | |
| Plant parts | Root | |
| Other cancers | Breast cancer, Squamous cell cancer,Liver cancer , Prostate cancer , and Colon cancer | |
| Target gene or protein | PGE(2) | |
| Gene or Protein evidence | It also inhibits PGE(2) production, indicating that suppression of tumor cell growth may be due to its ability to inhibit COX-2 activity. | |
| Target pathways | NA | |
| IC50 | 0.9 mg/mL against MCF-7 | |
| Potency | Scutellaria baicalensis could be promising as a therapeutic agent or an adjuvant to the conventional therapeutic modalities for cancers. | |
| Cell line/ mice model | HepG2, MCF-7, PC-3, LNCaP, KM-12, HCT-15, KB, SCC-25 | |
| Additional information | Scutellaria baicalensis also inhibits PGE(2) production, indicating that suppression of tumor cell growth may be due to its ability to inhibit COX-2 activity. | |
| PubChem ID | NA | |
| Additional PMIDs | 12470437 19836937 | |
| Additional sources of information | https://powo.science.kew.org/taxon/urn:lsid:ipni.org:names:458155-1 | |
| Safety | NA |